Semaglutide – Lyophilized Peptide Powder

Product Name: Semaglutide

CAS No.: 910463-68-2

Purity: >99.0%

Molecular Formula: C187H291N45O59

Molecular Weight: 4113.58 g/mol

Application: Weight loss / Type 2 Diabetes Management

Appearance: White Lyophilized Powder

Reconstitution: Required

Storage: After reconstitution, store at 2°C – 8°C

Description:

Semaglutide is a long-acting GLP-1 (glucagon-like peptide-1) receptor agonist that mimics the natural hormone involved in glucose regulation and appetite suppression. It is designed to lower blood sugar levels by enhancing insulin secretion, inhibiting glucagon release, and slowing gastric emptying. Semaglutide is clinically proven to reduce body weight and improve glycemic control in individuals with obesity or type 2 diabetes.

Approved for chronic weight management and T2D treatment, semaglutide works by activating GLP-1 receptors, enhancing satiety signals, and reducing caloric intake. In clinical trials, once-weekly administration of semaglutide has demonstrated significant reductions in body weight — with patients losing up to 15% or more of their starting weight at higher doses.

Clinical Data Highlights:

In the STEP clinical trial program, semaglutide 2.4 mg led to an average weight reduction of up to 14.9% over 68 weeks.

A higher proportion of participants achieved ≥5%, ≥10%, and ≥15% weight loss compared to placebo.

Improvement in glycemic markers including fasting glucose, HbA1c, and insulin sensitivity.

Product Functions:

Slows gastric emptying, enhancing satiety and reducing food intake

Stimulates insulin secretion in response to elevated glucose

Suppresses glucagon secretion during hyperglycemia

Lowers both fasting and postprandial blood glucose levels

Reduces HbA1c and supports long-term glycemic control

Promotes significant, sustained weight loss

May reduce risk factors for cardiovascular disease by improving lipid profiles and reducing inflammation

Enhances leptin sensitivity and may influence fat metabolism

Safety Profile:

Semaglutide is generally well-tolerated. The most common side effects are gastrointestinal (nausea, vomiting, diarrhea), particularly during dose escalation. These typically diminish over time with continued use.